Topical preparations for the treatment of seborrhea and process for inhibiting sebum production

US4439418A · kind A · utility

Assignee

• Henkel AG & Co. KGaA · DE

Inventors

• Hinrich Moller · Monheim, DE
• Siegfried Wallat · Monheim, DE
• Friedhelm Bartnik · Düsseldorf, DE

Key dates

• Filing date: Dec 9, 1981
• Grant date: Mar 27, 1984
• Expiry date: Dec 9, 2001

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61Q19/008
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A topical cosmetic preparation for the treatment of seborrhea containing an antiseborrheically effective amount of at least one compound having the formula ##STR1## wherein Ar represents a member selected from the group consisting of phenyl, phenyl substituted with at least one group selected from the group consisting of alkyl having from 1 to 4 carbon atoms, alkoxy having from 1 to 4 carbon atoms, hydroxy and halo, naphthyl and heteroaromatic radical having from 4 to 5 carbon atoms in the cycle, and R represents a member selected from the group consisting of hydrogen, alkyl having from 1 to 4 carbon atoms, alkanoyl having from 1 to 4 carbon atoms, aryl and arylcarbonyl, where aryl has the same meaning as Ar, as an antiseborrheic, and further containing conventional vehicles and additives. The invention also relates to the process for reducing sebaceous cell sebum production employing said topical cosmetic preparation.