Amidobenzamides, their salts and pharmaceutical compositions containing them

US4439444A · kind A · utility

Assignee

• Sanofi · FR

Inventors

• Dino Nisato · Pavia, IT
• Sergio Boveri · Tortona, IT
• Alberto Bianchetti · Milano, IT
• Romeo Roncucci · Zottegem, BE
• Paolo Carminati · Pomezia, IT

Key dates

• Filing date: Jul 7, 1982
• Grant date: Mar 27, 1984
• Expiry date: Jul 7, 2002

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Amidobenzamides acting as histamine H.sub.2 receptors blocking agents, of formula ##STR1## wherein A is CO or SO.sub.2 and B is alkyl, phenyl, pyridyl, pyridyl-1-oxyde, pyrazinyl or thienyl; their salts; process for their preparation by reaching 2-(5-dimethyl-aminomethylfuran-2-ylmethylthio)ethylamine with a derivative of formula ##STR2## and optional salification and pharmaceutical compositions containing same.