Patent · US Expired

Isolation of [S-(R, S]-1-(3-acetylthio-3-benzoyl-2-methylpropionyl)-L-proline from a diastereomeric mixture

US4439611A · kind A · utility

2Cited by

2References

6Claims

0Family size

Assignee

American Cyanamid Company · US

Inventors

Sivaraman Raghu · Norwalk, US
Robert J. Proverb · Danbury, US
Steven L. Peake · New Canaan, US

Key dates

Filing date	Jun 28, 1982
Grant date	Mar 27, 1984
Priority date	—
Expiry date	Jun 28, 2002

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D207/16
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

This disclosure describes continuous epimerization-crystallization process for the isolation of [S-(R*, S*)]-1-(3-acetylthio-3-benzoyl-2-methylpropionyl)-L-proline from a diasteromeric mixture thereof with [S-(R*, R*)]-1-(3-acetylthio-3-benzoyl-2-methylpropionyl)-L-proline.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.