Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents
US4440779A · kind A · utility
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14Claims
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Key dates
| Filing date | Jun 4, 1982 |
| Grant date | Apr 3, 1984 |
| Priority date | — |
| Expiry date | Jun 4, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Tricyclic derivatives of substituted pyrrole acids, e.g., substituted 4,10-dihydro-10-oxo-1H-[1]benzoxepino[4,3-b]pyrrole-2-acetic acids or the 5-thia analogs thereof have been prepared via hydrolysis of a precursor or decarboxylation of a precursor-diacid. These tricyclic compounds are found to have high analgesic and anti-inflammatory activities but low ulcerogenic side effects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.