Process for the preparation of plasminogen and plasminogen thus prepared

US4442213A · kind A · utility

Assignee

• Behringwerke Aktiengesellschaft · DE

Inventors

• Helmut Heber · Marburg, DE
• Horst Schwinn · Mainz, DE
• Norbert Heimburger
• Gerhardt Kumpe · Wetter, DE
• Manfred Schick · Frankfurt am Main, DE

Key dates

• Filing date: May 12, 1982
• Grant date: Apr 10, 1984
• Expiry date: May 12, 2002

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y304/21007
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

What is disclosed is a process for rendering plasminogen virtually free of hepatitis virus by heating a plasminogen solution in the presence of a proteinase inhibitor with plasmin specificity, an amino acid, and a saccharide or sugar alcohol.