Aldose reductase inhibitory pyrrole derivatives
US4443465A · kind A · utility
3Cited by
4References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 11, 1982 |
| Grant date | Apr 17, 1984 |
| Priority date | — |
| Expiry date | May 11, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides an aldose reductase inhibitory pyrrole derivative of the formula: ##STR1## in which Ra is an optionally substituted benzyl or cinnamyl radical, and ring A is the benzene ring of an optionally substituted benzo[b]thiophene, benzo[b]furan, quinoline or N-alkylquinolone, together with pharmaceutically acceptable salts and non-toxic biodegradable precursors thereof. The compounds of formula I are useful in the treatment of prophylaxis of the side-effects of diabetes or galactosemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.