Antihypercholesterolemic compounds
US4444784A · kind A · utility
270Cited by
15References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 18, 1980 |
| Grant date | Apr 24, 1984 |
| Priority date | — |
| Expiry date | Dec 18, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D309/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
6(R)-[2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)-polyhydronaphthyl-1')-ethyl]-4 (R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitors of the biosynthesis of cholesterol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.