Process for making human antibody producing B-lymphocytes
US4444887A · kind A · utility
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29Claims
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Key dates
| Filing date | Mar 12, 1981 |
| Grant date | Apr 24, 1984 |
| Priority date | — |
| Expiry date | Mar 12, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/11
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Antibody producing human B-lymphocytes are produced by a process which comprises culturing human B-lymphocytes in a tissue culture medium in the presence of an antigen; helper signal producing agents comprising monocytes or monocyte conditioned medium containing Interleukin 1 (I1-1), and helper T-lymphocytes or helper T-lymphocyte replacing factor; and human serum; and thereafter recovering the antibody producing cells from the medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.