Patent · US Expired

Prostanoid compounds and pharmaceutical compositions

US4447428A · kind A · utility

14Cited by
4References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 15, 1983
Grant dateMay 8, 1984
Priority date
Expiry dateJul 15, 2003

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D317/16
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Prostanoid compounds are described having the formula: ##STR1## where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated; X is --CH.dbd.CH--or --(CH.sub.2).sub.2 --; R is alkyl having a terminal --COOH or ester group; and Y is amino or substituted amino, particularly heterocyclic amino. The compounds have bronchodilator activity and/or inhibit blood platelet aggregation. The preparation and pharmaceutical formulation of the compounds is also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.