Process for the preparation of 1,3,7-trialkyl xanthines and di(3,7-dimethylxanthin-1-yl)methane as a medicament
US4450163A · kind A · utility
4Cited by
4References
3Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 2, 1981 |
| Grant date | May 22, 1984 |
| Priority date | — |
| Expiry date | Oct 2, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparation of 1,3,7-trialkyl xanthines, i.e. xanthines completely substituted on the nitrogen atoms, by the N-alkylation of xanthines by phase transfer catalysis. Some of the trialkyl xanthines obtained are new and di(3,7-dimethylxanthin-1-yl)methane is described as a medicament having immunosupressant properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.