Antihypercholesterolemic compounds
US4450171A · kind A · utility
120Cited by
11References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 14, 1982 |
| Grant date | May 22, 1984 |
| Priority date | — |
| Expiry date | Jun 14, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D309/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
6(R)-[2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)-polyhydronaphthyl-1')-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H- pyran-2-ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitors of the biosynthesis of cholesterol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.