16.beta.-Methyl steroid process
US4451404A · kind A · utility
1Cited by
3References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 9, 1983 |
| Grant date | May 29, 1984 |
| Priority date | — |
| Expiry date | Feb 9, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J17/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
.DELTA..sup.4 -3-keto, .DELTA..sup.1,4 -3-keto and 3.beta.-hydroxy 17-keto steroids (I) are transformed into the corresponding 16-.beta.-methyl-17-keto steroids (IV) by first activating the C-16 position, then methylating. By protecting the C-3 position of the .DELTA..sup.4 -3-keto and 3.beta.-hydroxy steroids the yields are greatly increased.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.