Patent · US Expired

Composition for binding bioactive substances

US4451568A · kind A · utility

77Cited by
12References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 13, 1981
Grant dateMay 29, 1984
Priority date
Expiry dateJul 13, 2001

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T428/31536
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

An acrylic-acid- based photopolymerizable composition is prepared which is capable of binding bioactive substances after being photopolymerized. The composition may be applied as a coating on a carrier substrate, photopolymerized and a bioactive substance fixed thereto. The composition adheres well to any usual carrier substrates, and its degree of hydrophilicity and permeability can be adapted to needs. The composition contains acrylic acid, a photoinitiator which is an aromatic ketone compound, a photopolymerization activator and adhesion promotor which is an amino-alcohol, acrylate or methacrylate, and a copolymerizable olefinic monomer which contains a reactive functional group capable of binding bioactive substances. The olefinic monomer is preferably N-hydroxysuccinimide acrylate, N-hydroxysuccinninimde amidocaproate, epoxypropyl acrylate or 2-isocyanato-ethyl acrylate.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.