Magnetic iron-dextran microspheres
US4452773A · kind A · utility
455Cited by
13References
31Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 5, 1982 |
| Grant date | Jun 5, 1984 |
| Priority date | — |
| Expiry date | Apr 5, 2002 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2446/86
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention relates to colloidal sized particles composed of magnetic iron oxide (Fe.sub.3 O.sub.4) coated with a polysaccharide, preferably dextran, or a derivative thereof having pendant functional groups. The particles have a magnetic moment, are electron dense, and are stable and non-aggregating under physiological conditions. They can be covalently bonded to antibodies, enzymes and other biological molecules and used to label and separate cells, cellular membranes and other biological particles and molecules by means of a magnetic field.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.