Method and device for mass transfer operation in immunoassays and other applications
US4454231A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 4, 1980 |
| Grant date | Jun 12, 1984 |
| Priority date | — |
| Expiry date | Dec 4, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/817
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention relates to a new technique and device for mass transfer of one or more components from one liquid phase to another liquid phase, involving a physical separation of said two phases. According to the new technique, the mass transfer and physical separation are carried out in the same device. The device consists of a mixing-reservoir into which is fitted snugly a mixer-separator, having a channel in the vertical axis of the mixer-separator. The two substantially immiscible liquid solutions are introduced into the mixing reservoir, the phases are thoroughly mixed, by moving the mixer-separator in and out the mixing reservoir. After the spontaneous separation into an upper and lower phase, the upper phase is removed by pushing in the mixer-separator said upper phase being accumulated in a collecting container. The new technique and device can be successfully utilized in the general field of liquid-liquid extraction and particularly applied in immunoassays, where the two basic operations of mass transfer and physical separation of fractions are required.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.