Preparation of hetaryloxyacetamides

US4455428A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Hans-Joachim Diehr · Wuppertal, DE
• Uwe Priesnitz · Solingen, DE

Key dates

• Filing date: Nov 18, 1982
• Grant date: Jun 19, 1984
• Expiry date: Nov 18, 2002

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of a hetaryloxyacetamide of the formula ##STR1## in which R.sup.1 is an optionally substituted oxazole, thiazole or tetrazole radical, comprising reacting a hydroxyacetamide of the formula ##STR2## with a halogeno-hetarene of the formula EQU R.sup.1 --Hal in which PA1 Hal represents a fluorine, chlorine, bromine or iodine atom, in the presence of solid, anhydrous potassium hydroxide and in the presence of an aprotic diluent at a temperature between about -50.degree. and +50.degree. C.