Preparation of hydrazidines

US4456769A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Gerhard Bonse · Neunburg vorm Wald, DE
• Thomas Schmidt · Neustadt, DE

Key dates

• Filing date: Jun 14, 1982
• Grant date: Jun 26, 1984
• Expiry date: Jun 14, 2002

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C257/22
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A new one-step process for the preparation of hydrazidines of the general formula ##STR1## in which R represents an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group or an optionally substituted aralkyl group, or their acid addition salts, in high yield comprises reacting iminoalkyl ethers of the general formula ##STR2## in which R has the abovementioned meaning and PA1 R.sup.1 represents an optionally substituted alkyl group or an optionally substituted cycloalkyl group, or their acid addition salts, with hydrazine in solvents under reduced pressure and at temperatures between -80.degree. and +100.degree. C., the reaction being effected in the presence of water present in the solvent and/or in the hydrazine by employing it as hydrazine hydrate. The hydrazidines of formula (I) and their salts are valuable intermediates in heterocyclic chemistry, for example for the synthesis of herbicidally active as-triazinones.