Babesiosis vaccine prepared from soluble parasitic antigen factors isolated from disintegration of Babesia infected erythrocites
US4457915A · kind A · utility
3Cited by
3References
42Claims
0Family size
Inventors
Key dates
| Filing date | Oct 15, 1982 |
| Grant date | Jul 3, 1984 |
| Priority date | — |
| Expiry date | Oct 15, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/018
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a method of preparation of a babesiosis vaccine which involves treating a suspension of Babesia infected erythrocytes. The erythrocytes are disintegrated, separated into soluble and insoluble fractions and subsequently fibrinogen and contaminated Babesia antigen is removed from the soluble fraction. The residual soluble fraction is then combined with an adjuvant to form the babesiosis vaccine. The invention also includes within its scope a vaccine derived from the abovementioned method and a method of administration of the vaccine to cattle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.