4a-Substituted avermectin compounds
US4457920A · kind A · utility
25Cited by
6References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 4, 1982 |
| Grant date | Jul 3, 1984 |
| Priority date | — |
| Expiry date | Aug 4, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/01
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are disclosed novel avermectin compounds wherein the 4-methyl group is substituted with hydroxy or various groups connected through the hydroxy oxygen atom. The hydroxy compounds are prepared by oxidation of the 4-methyl group and the hydroxy substituents prepared by a substitution process selective for primary alcohols. The compounds have utility as antiparasitic agents and compositions for that use are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.