Process for 1-oxa-.beta.-lactams
US4458071A · kind A · utility
1Cited by
2References
9Claims
0Family size
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Key dates
| Filing date | Nov 16, 1982 |
| Grant date | Jul 3, 1984 |
| Priority date | — |
| Expiry date | Nov 16, 2002 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An azetidin-2-one-4-sulfinic acid represented by the formula ##STR1## is reacted with Pb(OAc).sub.4 in liquid SO.sub.2 containing CuII ion to provide isomeric cyclization products of the formulas ##STR2## wherein R is e.g. benzyl, phenoxymethyl, benzyloxy, diphenylmethoxy, and R.sub.1 is a carboxy-protecting group. The products of the process are useful intermediates for 1-oxa-.beta.-lactam antibacterials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.