Method for the removal of interfering substances, including caffeine, in theophylline assays
US4460695A · kind A · utility
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9Claims
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Key dates
| Filing date | Dec 24, 1981 |
| Grant date | Jul 17, 1984 |
| Priority date | — |
| Expiry date | Dec 24, 2001 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/255
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for the separation of theophylline and caffeine contained in body fluids is provided. A macroreticular styrene-divinylbenzene copolymer resin activated by a protic solvent is utilized. The body fluid is eluted with water in an isocratic manner to afford a theophylline sample uncontaminated with caffeine. Such samples are useful in immunoassay procedures for the measurement of theophylline.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.