Aminoacridine-.alpha., .beta.-(D)- or -(L)-N-glycoside derivatives, the salts thereof and a process for the preparation of such compounds
US4462993A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 1, 1982 |
| Grant date | Jul 31, 1984 |
| Priority date | — |
| Expiry date | Mar 1, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel aminoacridine-.alpha.,.beta.-(D)- and -(L)-N-glycoside derivatives, the salts thereof and to a novel process for the preparation of such compounds and salts. The novel compounds have the formula I ##STR1## wherein R is hydrogen or a group of the formula II ##STR2## wherein n=0 or 1, p=1 or 2, A.sup.-p is an anion, preferably halogenide, R.sup.1 is hydrogen or a methyl group and PA1 R.sup.2 is hydrogen or a sugar residue, or R is dimethylamine, and the two substituents PA1 X and X.sup.1 are identical or different and stand for hydrogen, a group of the formula II, dimethylamine, halogen, a C.sub.1-4 alkyl group, a C.sub.1-4 alkoxy group, for a nitro-, cyano-, carbomethoxy-, carbamoyl-, phenyl- or a C.sub.1-4 alkylphenyl group, PA1 with the restriction that at least one of the substituents R, X and X.sup.1 represents a group of formula II with R.sup.2 =sugar residue, and PA1 R.sup.3 is hydrogen or a C.sub.1-5 alkyl group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.