Patent · US Expired

Antiinflammatory pyrazole thioureas

US4465685A · kind A · utility

1Cited by
1References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 15, 1981
Grant dateAug 14, 1984
Priority date
Expiry dateDec 15, 2001

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of formula (I) ##STR1## inhibit both the cyclo-oxygenase and lipoxygenase pathways of arachidonic acid oxygenation and are useful in medicine as, e.g., anti-inflammatory and anti-asthmatic agents. The compounds may be administered as the raw chemical or in association with a carrier as a pharmaceutical formulation. The compounds may be prepared by methods analogous to those known in the art, e.g. by the method of Duffin and Kendall in J. Chem. Soc. (1954), 408-415, or by other methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.