Carrier liquid solutions for the production of gas microbubbles, preparation thereof, and use thereof as contrast medium for ultrasonic diagnostics

US4466442A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Juergen Hilmann · Berlin, DE
• Rolf Hoffmann · Brasschaat, BE
• Wolfgang Muetzel · Berlin, DE
• Ingfried Zimmermann · Berlin, DE

Key dates

• Filing date: Oct 13, 1982
• Grant date: Aug 21, 1984
• Expiry date: Oct 13, 2002

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K49/223
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The useful lifetime and the amount of microbubbles of a size less than 50 .mu.m produced by mechanical agitation of an aqueous liquid employed as an ultrasonic contrast medium are increased by employing a liquid containing dissolved therein a tenside which reduces the surface tension of the liquid and a compound which raises the viscosity of the liquid.