Process for producing interferon inducers
US4469685A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 5, 1983 |
| Grant date | Sep 4, 1984 |
| Priority date | — |
| Expiry date | May 5, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K36/8965
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for producing interferon inducers from the plants, comprising extracting a water-soluble interferon inducer with water from the tissue of a plant selected from the genera Atractylodes, Lonicera, Plantago, Lithospermum, Ligusticum, Cnidium, Bupleurum, Notopeterygium, Heracleum, Aralia, Panax, Polygala, Sophora, Euchresta, Astragalus, Sinomenium, Stephania, Cocculus, Cimicifuga, Rheum, Gastroida, Asparagus, Pinellia, Evoida and variants thereof capable of producing said interferon inducer at a temperature of from ambient to the boiling point of the extraction mixture for a period sufficient to extract the major portion of said interferon inducer present in the plant tissue, forming a supernatant, fractionating the supernatant to yield fractions containing the major portion of said interferon inducer in the supernatant and recovering said interferon inducer therefrom. Preferably, the fractionation may be effected by ultrafiltration. The interferon inducers thus obtained have a molecular weight of from about 30,000 to about 3,000,000 and are of potential interest for preventing and treating various diseases of humans and animals caused by viral infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.