Analgesic composition and use thereof to ameliorate deep and intractable pain

US4469702A · kind A · utility

Inventor

• Thomas Schulte · Paderborn, DE

Key dates

• Filing date: Jan 10, 1983
• Grant date: Sep 4, 1984
• Expiry date: Jan 10, 2003

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/235
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Deep and intractable pain is ameliorated by the topical application proximate the situs of the pain of an analgesic amount of an aqueous mixture of biphenamine and a water soluble skin penetrant, e.g., DMSO or propylene glycol, in a pharmaceutically acceptable carrier, the concentration of biphenamine and skin penetrant in the mixture each being ineffective to ameliorate the pain when applied separately from the other to the situs. The mixture is also useful for the amelioration of pathological conditions of the skin and other topical areas of the body, e.g., those caused by viral, bacterial, fungal and other microorganism infections and those having associated localized inflammatory response which cause itching or pain, e.g., wounds and burns.