1,3-Disubstituted imidazoles
US4469865A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Sep 24, 1982 |
| Grant date | Sep 4, 1984 |
| Priority date | — |
| Expiry date | Sep 24, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
1,3-Disubstituted imidazoles of the general formula (I): ##STR1## wherein A and B may be the same or different, and each is a straight- or branched-chain alkylene or alkenylene group having 1 to 8 carbon atoms, Y is an acyl group having 2 to 10 carbon atoms, an alkoxycarbonyl group having 2 to 7 carbon atoms or an dialkoxymethyl group having 3 to 13 carbon atoms, Z is a cyano group or an alkoxycarbonyl group having 2 to 7 carbon atoms, X is a halogen atom, n is zero or 1. The said compounds are intermediates for producing the imidazole derivatives of the general formula (V) above which possess strong and specific inhibitory effects on thromboxane synthetase and thus are useful as therapeutical agents for treatment of diseases caused by thromboxane A.sub.2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.