Method of increasing oral absorption of .beta.-lactam antibiotics
US4470980A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 25, 1981 |
| Grant date | Sep 11, 1984 |
| Priority date | — |
| Expiry date | Jun 25, 2001 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and drug form are provided for increasing the oral absorption of .beta.-lactam antibiotics such as the penicillins, cephalosporins and related chemical species by the oral administration of said .beta.-lactam antibiotics in a suitable pharmaceutically accepted excipient to which has been added a hydroxy aryl or hydroxy aralkyl acid or salt, amide or ester thereof. The hydroxyaryl or hydroxyaralkyl acid or salt, amide or ester thereof is present in the drug form in quantities sufficient to be effective in enhancing the rate of oral absorption of the .beta.-lactam antibiotic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.