Esters
US4470997A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1982 |
| Grant date | Sep 11, 1984 |
| Priority date | — |
| Expiry date | Sep 9, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns di- and tri-esters derived from alkanoic, (cycloalkyl)alkanoic, benzoic or phenylalkanoic acids with N-(acylaminoalkyl)-dihydroxyphenylethanolamines, and pharmaceutically acceptable salts thereof; processes for their preparation and manufacture; and pharmaceutical compositions thereof. The esters are useful for the topical treatment of an area of inflammation affecting the skin of a warm-blooded animal. Representative esters of the invention are 1-[3,4-bis(pivaloyloxy)phenyl]-2-[2-(2-phenylacetamido)ethylamino]-ethanol , 1-[3,4-bis(pivaloyloxy)phenyl]-2-[1,1-dimethyl-2-(2-phenoxyacetamido)ethy lamino]-ethanol, and the hydrochlorides and hydrobromides thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.