Pharmaceutical compositions capable of increasing cerebral serotonin concentration
US4472387A · kind A · utility
6Cited by
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7Claims
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Key dates
| Filing date | Sep 16, 1982 |
| Grant date | Sep 18, 1984 |
| Priority date | — |
| Expiry date | Sep 16, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition suitable for increasing cerebral serotonin concentration, comprising a serotonin precursor selected from the group consisting of 5-hydroxytryptophan and derivatives of 5-hydroxytryptophan having the formula: ##STR1## wherein R represent hydrogen; a C.sub.1 -C.sub.12 alkyl group; or a C.sub.5 -C.sub.16 alicyclic, monocyclic aromatic hydrocarbyl, or polycyclic aromatic hydrocarbyl group; and a nitrogenous heterocyclic compound selected from the group consisting of inosine, theophylline, theobromine, allopurinol, pyridoxine, hypoxanthine, folic acid, adenine, nicotinamide, caffeine, and orotic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.