Patent · US Expired

Triazoloquinazolones having antihistaminic and bronchospasmolytic activity

US4472400A · kind A · utility

6Cited by
8References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 21, 1982
Grant dateSep 18, 1984
Priority date
Expiry dateSep 21, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D239/96
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel triazoloquinazolones of the formula ##STR1## wherein R and R' are individually selected from the group consisting of hydrogen, halogen, nitro and alkyl and alkoxy of 1 to 3 carbon atoms, Y is selected from the group consisting of alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 4 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, aryl of 6 to 8 carbon atoms and aralkyl of 7 to 8 carbon atoms, B is an alkylene of 1 to 3 carbon atoms, X is selected from the group consisting of ##STR2## R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, aryl of 6 to 8 carbon atoms, aralkyl of 7 to 8 carbon atoms, aminoalkyl of 2 to 4 carbon atoms, mono- and dialkylaminoalkyl with each alkyl having 2 to 4 carbon atoms, piperidinoalkyl of 1 to 4 alkyl carbon atoms, morpholinoalkyl of 1 to 4 alkyl carbon atoms and piperazinylalkyl of 1 to 4 alkyl carbon atoms or R.sub.1 and R.sub.2 taken together with the nitrogen to which they are attached form a saturated mono- or bicyclic heterocyclic ring with 4 to 8 carbon atoms optionally substituted with 1 to 2 methyls and optionally containing in the ring a heteroa…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.