Prostaglandin E.sub.1 analogues
US4473587A · kind A · utility
1Cited by
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11Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 21, 1983 |
| Grant date | Sep 25, 1984 |
| Priority date | — |
| Expiry date | Jul 21, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0015
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Prostaglandin E.sub.1 analogues of the general formula: ##STR1## (wherein R.sup.1 represents a single bond or a straight- or branched-chain alkylene group of from 1 to 5 carbon atom(s), R.sup.2 represents a cycloalkyl group of from 4 to 7 carbon atoms either unsubstituted or substituted by at least one straight- or branched-chain alkyl group of from 1 to 8 carbon(s), and the double bond between C.sub.13 and C.sub.14 is trans) and cyclodextrin clathrate thereof, are useful in the prevention or treatment of cytodamage associated with digestive system disease, especially liver damage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.