Patent · US Expired

7,6 Dioxo-4H,6H-pyrano[3,2-g]quinoline dicarboxylic acids and anti-allergic use thereof

US4474787A · kind A · utility

11Cited by
2References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 2, 1982
Grant dateOct 2, 1984
Priority date
Expiry dateFeb 2, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/24
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There are described compounds of formula I ##STR1## in which an adjacent pair of R.sub.5, R.sub.6, R.sub.7 and R.sub.8 form a chain --COCH.dbd.CE--O--, and the remainder of R.sub.5, R.sub.6, R.sub.7 and R.sub.8, which may be the same or different, each represent hydrogen, hydroxy, alkyl, halogen, alkenyl, alkoxy, or --NR.sub.1 R.sub.2 in which R.sub.1 and R.sub.2, which are the same or different, are each hydrogen or alkyl, PA1 Rg is hydrogen, alkyl, alkenyl or phenyl-alkyl, and PA1 E is --COOH, a 5-tetrazolyl group or an (N-tetrazol-5-yl) carboxamido group, PA1 and pharmaceutically acceptable derivatives thereof. There are also described processes for making the compounds and pharmaceutical, e.g. anti-allergic, compositions containing the compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.