Patent · US Expired

Recombinant monoclonal antibodies

US4474893A · kind A · utility

372Cited by
16References
50Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 1, 1981
Grant dateOct 2, 1984
Priority date
Expiry dateJul 1, 2001

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/864
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Antibodies having binding affinity for two desired antigens, hereinafter "recombinant monoclonal antibodies"; recombinant monoclonal antibodies produced by a quadroma cell or a trioma cell; and methods for producing recombinant monoclonal antibodies by means of a quadroma cell or a trioma cell, wherein a quadroma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a hybridoma cell which produces an antibody having specific binding affinity for another desired antigen, and wherein a trioma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a lymphocyte which produces an antibody having specific binding affinity to another desired antigen.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.