Patent · US Expired

Apovincaminic acid esters

US4474960A · kind A · utility

3Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 11, 1982
Grant dateOct 2, 1984
Priority date
Expiry dateJun 11, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D461/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A process is disclosed for the preparation of racemic cis or trans apovincaminic acid esters of the formula (I) ##STR1## and the corresponding optically active derivatives of the formulae (Ia) ##STR2## wherein R.sup.1 and R.sup.2 are identical or different alkyl groups having 1 to 6 carbon atoms. Apovincaminic acid alkyl esters are well-known vasodilating compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.