Dimers of peptide amides
US4476117A · kind A · utility
1Cited by
5References
8Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 15, 1982 |
| Grant date | Oct 9, 1984 |
| Priority date | — |
| Expiry date | Dec 15, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula: ##STR1## wherein R.sup.1 and R.sup.2 stand for alk-2-enyl radicals of not more than 6 carbon atoms, A stands for Gly or Azgly, B stands for Leu or Met, J stands for --(CH.sub.2).sub.n --, wherein n stands for an integer from 1 to 10, or a phenylene radical, and pharmaceutically-acceptable acid-addition salts thereof. Processes for the manufacture of the compounds. Pharmaceutical compositions comprising one of the compounds and a pharmaceutical diluent or carrier. The compounds are selective .delta.-opiate-receptor antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.