Patent · US Expired

2-Aryltetraazaindenes for treating cardiac insufficiency

US4477454A · kind A · utility

6Cited by

4References

7Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Rochus Jonas · Darmstadt, DE
Michael Kloft · Weiterstadt, DE
Hanns Wurziger · Darmstadt, DE
Juergen Harting · Darmstadt, DE
Hans-Joachim Enenkel · Darmstadt, DE
Klaus-Otto Minck · Ober-Ramstadt, DE
Hans-Jochen Schliep · Traisa, DE

Key dates

Filing date	May 9, 1983
Grant date	Oct 16, 1984
Priority date	—
Expiry date	May 9, 2003

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C65/28
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

2-Aryltetraazaindenes of the formula ##STR1## wherein --A-- is --N.dbd.CH--CH.dbd.N-- or --CH.dbd.N--N.dbd.CH--, Ar is unsubstituted phenyl or phenyl mono-, di- or tri-substituted by hydroxyl, mercapto, dialkylamino, trifluoromethyl and/or --Z--R groups, Z is --O--, --S-- or --SO-- and R is alkyl, alkenyl, alkynyl or cyanomethyl, the alkyl, alkenyl and alkynyl groups each having up to 5 C atoms, and their physiologically acceptable salts, exhibit blood pressure, myocardial contraction, and anti-ulcer activities.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.