Renin inhibitors
US4478827A · kind A · utility
14Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 9, 1983 |
| Grant date | Oct 23, 1984 |
| Priority date | — |
| Expiry date | May 9, 2003 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/86
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of the formula EQU Z-His-Pro-Phe-His-X-X-Val-Tyr-(D-)-Y wherein the Xs are the same or different and selected from the group consisting of an aromatic, a chlorinated aromatic, an aliphatic and a chlorinated aliphatic amino acid residue; PA1 Y is a positively or negatively charged amino acid residue; and PA1 Z is a proline or a polyprolyl residue having up to 5 prolyl residues, is useful for decreasing renin-related high blood pressure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.