Use of phosphotriester intermediates for preparation of functionalized liposomes
US4480041A · kind A · utility
54Cited by
4References
11Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 9, 1982 |
| Grant date | Oct 30, 1984 |
| Priority date | — |
| Expiry date | Jul 9, 2002 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/829
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of forming an analyte-functionalized liposome for use in immunoassay techniques employs a phosphotriester intermediate of a phospholipid derivatized with the desired analyte in a process of forming a liposome which is functionalized on its outer surface with the analyte and which carries an enzyme marker. The method is also used to functionalize the liposome with a ligand which acts as a leash between the analyte and the liposome. Liposomes produced by the method include penicillin-G-functionalized liposome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.