Des-proline vasopressin antagonists
US4481193A · kind A · utility
11Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 7, 1984 |
| Grant date | Nov 6, 1984 |
| Priority date | — |
| Expiry date | Mar 7, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/15
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Certain octapeptides, which have structures characterized by being a six unit cyclic peptide ring with a dipeptide tail with no proline unit, have vasopressin antagonist activity. An important species of the group is [1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid)-2-(O-ethyl-D-tyrosine)-4-valine]-7-desproline-8-arginine-vasopressin .
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.