Patent · US Expired

Des-proline-des-glycine vasopressin antagonists

US4481194A · kind A · utility

11Cited by
2References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 7, 1984
Grant dateNov 6, 1984
Priority date
Expiry dateMar 7, 2004

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/15
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Certain heptapeptides which have structures characterized by being a six unit cyclic peptide ring with an arginine or lysine tail have vasopressin antagonist activity. An important species of the group is [1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid)-2-(O-ethyl-D-tyrosine)-4-valine-7-desproline-8-arginine-9-desglycine ]-vasopressin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.