1-Phenethyl-alpha-phenyl-piperidine-3-propanenitriles and their pharmaceutical uses
US4481207A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 15, 1983 |
| Grant date | Nov 6, 1984 |
| Priority date | — |
| Expiry date | Aug 15, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/64
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 each represent a hydrogen atom, a halogen atom, a (C.sub.1-4)alkoxy radical, a (C.sub.1-4)alkylthio radical, a halogeno(C.sub.1-4)alkyl radical, a (C.sub.1-4)alkyl radical or a cycloalkyl-alkoxy-alkoxy radical or two of the adjacent R symbols together form a methylenedioxy or ethylenedioxy radical, R.sub.6 represents a hydrogen atom, a (C.sub.1-4)alkyl radical, a (C.sub.3-6)cycloalkyl radical or a (C.sub.3-6)cycloalkyl-(C.sub.1-4)alkyl radical, and R.sub.7, R.sub.8 and R.sub.9 each represent a hydrogen atom or a methoxy radical, are new compounds possessing pharmacological properties; they are useful as calcium antagonists and as antihypertensives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.