Composition of intravenous immune globulin
US4482483A · kind A · utility
39Cited by
5References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 2, 1983 |
| Grant date | Nov 13, 1984 |
| Priority date | — |
| Expiry date | Sep 2, 2003 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/861
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An intravenous immune globulin preparation having at least 99% pure globulin protein and an anticomplement activity of less than 0.10 C'50 units/mg IgG prepared by: precipitating impurities from Cohn Fraction II in an aqueous-alcohol medium at defined temperature and pH, removing the precipitated impurities, stabilizing the diluted solution with albumin, concentrating the solution and removing the alcohol therefrom. Also prepared by this method, an intravenous, hyperimmune globulin preparation having increased antibody titers to sixteen serospecific strains of Pseudomonas aeruginosa.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.