Antacid material based on magnesium aluminium hydroxide and the preparation thereof
US4482542A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 12, 1983 |
| Grant date | Nov 13, 1984 |
| Priority date | — |
| Expiry date | Jul 12, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a process for the preparation of an antacid material based upon magnesium aluminium hydroxide, wherein magnesium hydroxide and/or magnesium oxide is reacted in an atomic ratio of magnesium to aluminium of 1:1 to 3:1 with an aqueous solution of aluminium sulphate until the pH of the reaction mixture is from 4.0 to 8.0, whereafter water-soluble components are removed from the mixture in known manner and this is isolated and, if desired, dried. The present invention also provides pharmaceutical compositions containing an antacid material prepared by this process, in admixture with a conventional pharmaceutical adjuvant. Furthermore, the present invention provides a method of combating hyperacidity and gastrointestinal diseases, which comprises administering an antacid material prepared by the above process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.