Analgesic pharmaceutical compositions containing 5-phenyl-1,4-benzo diazepine compounds and a method of using same

US4482548A · kind A · utility

Assignee

• Kali-Chemie Pharma GmbH · DE

Inventors

• Dietmar Roemer · Pfullendorf, DE
• Michael Ruhland · Hannover, DE
• Horst Zeugner
• Wolfgang Milkowski
• Hans Liepmann · Hannover, DE

Key dates

• Filing date: May 16, 1983
• Grant date: Nov 13, 1984
• Expiry date: May 16, 2003

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Highly effective analgesic pharmaceutical compositions and methods of using same are described. Said compositions contain, as analgesic agent, a 5-phenyl-1H-2,3-dihydro-1,4-benzodiazepine compound of the formula ##STR1## wherein R.sub.1 indicates a substituent selected from the group consisting of hydrogen and lower alkyl, PA1 R.sub.2 indicates a substituent selected from the group consisting of hydrogen, lower alkyl, and lower alkanoyl, PA1 R.sub.3 indicates a substituent selected from the group consisting of hydrogen and halogen, and PA1 R.sub.4 indicates halogen, or a physiologically compatible acid addition salt thereof.