Immunoassay with antigen or antibody labeled liposomes sequestering enzyme
US4483921A · kind A · utility
43Cited by
14References
32Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 28, 1982 |
| Grant date | Nov 20, 1984 |
| Priority date | — |
| Expiry date | Apr 28, 2002 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/829
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An immunoassay method utilizes antigen tagged, enzyme encapsulating liposomes which are immunospecifically ruptured in the presence of cognate antibody and active complement. A homogeneous phase reaction occurs with the antibody and complement acting to release the enzyme if an immunospecific antigen-antibody complex is formed at the surface of the liposome. The positions of the antigen and antibody can be reversed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.