Device for isoelectric focusing
US4484141A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 12, 1982 |
| Grant date | Nov 20, 1984 |
| Priority date | — |
| Expiry date | Nov 12, 2002 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44713
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A device for detecting the isoelectric end point in an isoelectric focusing system by electronically integrating, over successive time intervals, a characteristic of the electrical input to said zone as it varies with the increasing resistance of the zone. Most conveniently, the measured characteristic is the current through the zone which, under constant impressed voltage or power, asymptotically approaches a minimum value as the end point is reached. The measured characteristic is continually converted to a sequence of pulses indicative of the value of the characteristic. The end point is indicated when the difference between counts of these pulses over successive time intervals reaches a preselected value. At the end point, provision is made for replacement of the focusing voltage with a lower voltage to keep the ampholytes focused. A signal can be activated at the end point.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.