Process for the production of .beta.-hydroxy-.alpha.-aminocarboxylic acids

US4486600A · kind A · utility

Assignee

• Degussa AG · DE

Inventors

• Axel Kleemann · Hanau, DE
• Bernd Lehmann · Cologne, DE
• Klaus Deller · Großkrotzenburg, DE

Key dates

• Filing date: Nov 16, 1983
• Grant date: Dec 4, 1984
• Expiry date: Nov 16, 2003

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C255/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

.beta.-hydroxy-.alpha.-aminocarboxylic acids of the formula: ##STR1## where R.sub.1 and R.sub.2 are hydrogen or an alkyl group having 1 to 10 carbon atoms are produced by hydrogenating the correspondingly substituted cyanohydrin in a water containing medium first in the presence of a hydrogenation catalyst and an acid at a temperature between -10.degree. and +40.degree. C. and a hydrogen pressure of less than 10 bar, until per mole of cyanohydrogen employed one mole of hydrogen is taken up and then employing the solution obtained as starting material for a Strecker or Bucherer synthesis of an amino acid.