Polymeric active methylene compounds
US4489197A · kind A · utility
10Cited by
3References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 17, 1984 |
| Grant date | Dec 18, 1984 |
| Priority date | — |
| Expiry date | Feb 17, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S526/916
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Polymeric compounds which have recurring ##STR1## units, wherein X is N or O, R.sub.1, R.sub.2 and R.sub.3 are hydrogens or lower alkyls and R.sub.4 is ##STR2## and aromatic amine or an aromatic hydrazine which provides X as N. These polymers provide active methylene groups which serve as points of attachment for organic groups-particularly azo functionality-containing groups. These azo links can be cleaved by bacteria in the mammalian lower bowel, thereby releasing the corresponding amino groups. This mechanism can effect programmed delivery of pharmaceutically desirable species to the lower bowel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.