Patent · US Expired

Thiazolylurea derivatives, a process for preparing same and a pharmaceutical composition containing same

US4490393A · kind A · utility

4Cited by
3References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 17, 1982
Grant dateDec 25, 1984
Priority date
Expiry dateSep 17, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D277/54
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides thiazolyl derivatives as new chemical substance represented by the general formula: ##STR1## wherein R.sup.1 stands for a lower alkyl group or a substituted or unsubstituted phenyl group, R.sup.2 for a hydrogen atom, a lower alkyl, lower alkoxy or lower alkylthio group, and R.sup.3 for a pyridyl or iso-oxazolyl group or a grouping of the general formula: ##STR2## processes for preparing same and pharmaceutical compositions containing the thiazolyl derivatives. More particularly, the present invention provides new thiazolyl derivatives which possess immuno-modulating activity and are thus therapeutically effective against immunodiseases such as chronic rheumatoid arthritis and also useful against viral diseases or for the immunotherapy of cancers and possess properties desirous as medicines with a slight toxicity, processes for preparing same and pharmaceutical compositions containing the new substance.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.